Core technology

When the whole blood is mixed with reagents, the antibodies to which magnetic beads are bound and the antigen expressed
on the surface of cancer cells are specifically bound, and the surface of cancer cells is coated with magnetic nanobeads.

The GenoCTC device precisely controls the laminar flow within a microfluidic chip, preventing the blending of blood and buffer.

Cancer cells coated with magnetic beads, are specifically guided towards the buffer channel by the magnetized wire pattern chip, and separated specifically with minimal contamination of blood cells, yielding high purity CTCs.

Our platform

The GenoCTC is a fully automated device that allows the separation of circulating tumor cells (CTCs) from
blood samples, provided with disposable cartridges and reagent kits (EpCAMs) for CTC separation and the
GenoCTC Profiling Kit.

GenoCTC is a user-friendly device that does not require sample preparation, enabling sensitive, accurate
and high-purity isolation of CTCs from patient samples.

Performance

CTC isolation by GenoCTC involves microfluidic and immuno-magnetophoretic technology,
made feasible by our microfluidic separation chip, and ferromagnetic wire pattern chip.

GenoCTC allows isolation of CTCs based on cancer cell-specific biomarkers like EpCAM, MET, etc.
In the blood-based spiking test, we observe 80% recovery, 77% separation, and 90% purity.